Atelier Ayesha: The Alchemist of Dusk

The promise begins. After times of prosperity, people must endure the dusk. As another of period of dusk begins, in a region of the world where people are beginning to live humble lives once again… This land lacks the system of a governed nation, yet people live together, hand in hand. There, in an isolated workshop, lives a girl who makes a living by making medicine. This girl's name is Ayesha. She used to live with her grandfather and younger sister, but after her grandfather passed away a few years ago, her sister also went missing.